ea0094oc2.4 | Endocrine Cancer and Late Effects | SFEBES2023
Grunberg Nil
, Qian Jiani
, Tam Joseph
, Lorentzen Marc
, Winkler Mathias
, Ahmed Hashim
, Bevan Charlotte
, Fletcher Claire
Prostate Cancer (PC) affects 1-in-6 men in the UK, and obesity 1-in-3, with rates of both increasing. High-fat diet is linked with increased risk of PC death, and volume of peri-prostatic adipose tissue (PPAT) is associated with increased risk of lethal PC/reduced therapy response. Despite this, molecular mechanisms underpinning obesity-driven PC remain poorly-understood. This is important since weight-gain and central obesity are major side-effects of PC trea...